Dermatological aspects of cerebrovascular diseases

The affliction known commonly as ’stroke’ is the third most common cause of death in the developed world after cancer and ischemic heart disease (1). It is responsible for a large incidence of physical disabilities, and becomes more frequent with advancing age (2). The US annual incidence of acute cerebrovascular disease (CVD) is 700,000. Nearly 5 million stroke survivors are involved in personal health management today. CVD can cause death and disability either by ischemia from occlusion of the blood vessels or hemorrhage due to rupture (3). Acute focal stroke is characterized by the sudden appearance of a focal deficit of brain function, which most commonly lead to hemiplegia with or without signs of focal higher cerebral dysfunction such as aphasia, hemisensory loss, visual field defect or brain-stem deficit. Intimate mechanisms of dermatological reactions in stroke